Acute Kidney Injury

Market opportunity for Acute Kidney Injury (AKI)

  • AKI has become a nosocomial disease with an incidence of 5-7% in hospitalized patients
    • Surgery (especially post cardiac surgery)
    • Contrast-studies
  • 5-24-billion-dollar annual cost
  • Mortality of 45-70%
  • AKI is increasingly recognized in COVID-19 patients

ACE2 variant protects against AKI in the mouse model of ischemia reperfusion

  • This preliminary work was presented at the meeting of the American Society of Nephrology in November of 2019